Systemic Medication: Oxybutynin for episodic hyperhidrosis with hypothermia

The rare syndrome of episodic hyperhidrosis with hypothermia is thought to be due to an abnormality in the hypothalamus. A patient with this syndrome had relief of his extreme sweating when prescribed the anticholinergic oxybutynin for unrelated urinary urgency.[87]

Recently, the International Hyperhidrosis Society and two of its physician leaders conducted an in-depth webinar all about the use of oral medications, including oxybutynin, to treat a variety of types of hyperhidrosis. You can "